Understand and improve your laboratory results with our health dashboard. Older platelets are generally smaller than younger ones therefore, a low MPV may mean that a condition is affecting the production of platelets in the bone marrow. What Does It Mean If Your Mean Platelet Volume Result Is Too LowĪ low MPV indicates that the average platelet size is small. Also, the authors suggested that increased platelet activation might associate with cardiovascular risk in these patients. According to a 2010 study, MPV levels were higher in patients with psoriasis and psoriatic arthritis than controls. Reports of MPV in psoriatic arthritis are sporadic. Another group of authors reported lower MPV levels in patients with active lupus arthritis in comparison to SLE patients in remission or healthy controls. Of note, a positive correlation of MPV with albumin levels was documented. At a cutoff level of 8.32 fL, MPV sensitivity and specificity for detecting active disease were 86 and 41%, respectively. A Mexican study accounted for lower MPV levels in active lupus patients as compared to those with inactive disease. There has been a recent interest in MPV levels in patients with SLE. The authors suggested that MPV works as a negative marker in these patients. Overall, a low MPV level surrogated inflammatory states in a large number of rheumatic patients. An inverse correlation of MPV with ESR was also seen in lupus patients. MPV correlated negatively with both the BASDAI in ankylosing spondylitis and with CRP in psoriatic patients. An inverse correlation of MPV with erythrocyte sedimentation rate, C-reactive protein, and DAS-28 was found in RA patients. A recent study correlated MPV with inflammatory and disease indexes in rheumatic disorders. Mpv And Rheumatic DiseasesĪ low MPV is usually related to inflammatory states.

A low result may suggest more important health problems such as leukemia, human immunodeficiency virus, or bone marrow cancer.Įxtremely low values in the mean platelet volume create a great risk for the patient of suffering coagulation problems in case of trauma, that is, suffering a significant loss of blood in any wound or injury. If not, it determines if the value is low. Many laboratories display the normal reference range next to the test results.ĭetermine if your mean platelet volume value is high, possibly suggesting high blood pressure or other heart problems. Ī value below 5 or above 15 is cause for concern.Ĭompare your results to the normal range. The normal platelet count in an adult is in the range of 150,000 to 400,000 per microliter of blood, and a normal mean platelet volume value should be in the range of 5 to 15 femtoliters. Generally, both the MPV value and the platelet count per blood volume are included.

To understand the MPV value in a blood test You should look for the «VPM» indicator among the results of the tests you did in the laboratory.

Low mpv levels